Fondef Fund for the Promotion of Scientific and Technological

July, 2012. Through a novel technique a team of researchers from the School of Biological Sciences and Veterinary Sciences, University of Concepción obtained, after four months of testing, three copies of rodents. Source: Southern Conception

 

The world of science is revolutionized and is home to a team of researchers from the Schools of Biological Sciences and Veterinary Science UdeC, formed by academics by George Toledo, Oliberto Sanchez, Rafael Maura, Oscar Cabezas, Florence Hughes and Natalie Parra, created the first three transgenic mice, developed in Concepcion, which already have 23 days.

 

Obtaining these samples was achieved through the innovative technique called lentitransgénesis, that is mediated gene transfer vector. A method used by developed countries only.

This morning, researcher Biological Sciences faculty Jorge Toledo explained that unlike traditional techniques, in which the transfer of genetic material to the nucleus of an embryo is made by microinjection with microneedles that must get to the core- lentitransgénesis used in the "shell" of a special type of virus (lentivirus), carrying the DNA is to be incorporated into the embryonic cell.

 

One of the most significant achievements of this development is that mice can be used as an animal model to test the effectiveness of drugs aimed at treatment of human diseases, because of their special characteristics making them suitable for this task.

 

But this is only one of the possibilities offered by this technique, led to the production of larger transgenic animals, opens a wide range of biotechnological applications, since it is possible to obtain, through them, proteins of therapeutic or pharmacological.

 

On the other hand, Dr. Oliberto Sanchez another of the principal investigators of this development is the integration of a number of lines of research that has already been progress. Including, the development of a prototype vaccine for hantavirus or the production of follicle stimulating hormone used in assisted reproduction programs to encourage egg production.

 

To the Dean of Biological Sciences, Nelson Carvajal, the achievements of the researchers are a step closer to a goal that has raised the Faculty: "Carry the knowledge generated in our laboratories toward solving specific problems of men and, in this case, which are related to health ".

 

More information:

 

INNOVATE IN PROCESS TECHNOLOGY FOR …

Name: JORGE ROBERT TOLEDO ALONSO. Address: BARRIO UNIVERSITY S / N, ARCO BUILDING, FLOOR 3. CONCEPCION. Phone: 41-2661118 …

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